The thyroid gland is regulated by thyrotropic hormone from the anterior hypophysis body gland (Hypothyroidism, 2002). The hypothalamus releases a hormone called thyrotropic hormone releasing hormone (TRH) which acts on the anterior hypophysis and causes it to release TSH, which signals the thyroid to release thyroid hormones. The system works on a feedback loop controlled by the level of thyroid hormones in the bloodstream. If thyroid hormone levels in the blood drop, the ant
rior pituitary gland secretes more TSH; if the blood levels of thyroid hormones rise, the production of TSH by the anterior pituitary is turned off.
The major effect from removal of the anterior pituitary gland, and therefore loss of TSH, would be on the metabolic system, make a slow down of metabolism resulting in: lean gain, constipation, lethargy, dry skin and hair, intolerance to cold, depression, excessive sleepiness, muscle cramps, raised cholesterol levels, simplificationd concentration, and swelling of the legs, which are symptoms of hypothyroidism.
A decrease in FSH and LH from removal of the anterior pituitary gland would have equal effects on both the female and the male reproductive systems (Applegat
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